Devices and methods for producing planar polymeric materials using microfluidics

Primary Investigators:

A microfluidic device allows controllable incorporation of secondary biopolymers within a flowing biopolymer sheet followed by a cross-linking step that retains the microscale composition.

A microfluidic device to produce biopolymer sheets.

Axel Guenther, Milica Radisic

Description:

Methods and devices are disclosed for providing the controlled formation of planar homogeneous or heterogeneous materials using microfluidic devices. In one embodiment, a planar array of microfluidic channels is employed to produce a flowing liquid sheet having heterogeneous structure by spatially and temporally controlling dispensing of polymer liquid from selected microchannels. The resulting liquid sheet is solidified to produce a planar heterogeneous material that may be continuously drawn and/or fed from the plurality of microfluidic channels. The polymer liquid may include a payload that may be selectively incorporated into the heterogeneous structure. In some embodiments, the local material composition is controllable, thereby allowing control over local and bulk material properties, such as the permeability and the elasticity, and of creating materials with directionally dependent properties.

Publication:

Mosaic Hydrogels: One-Step Formation of Multiscale Soft Materials

Patent:

Devices and methods for producing planar polymeric materials using microfluidics

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